What is Cornelia de Lange Syndrome?

Cornelia de Lange Syndrome (CdLS) is a genetic disorder affecting 1 of every 10,000 births. CdLS is a disorder which can be caused by various genetic mutations. CdLS causes both skeletal and intellectual abnormalities. The number of possible causes, makes the disorder present uniquely in each individual.


CdLS is equally common amongst all races and genders.


CdLS is characterized by slow growth patterns before and after birth, although this may not be present in milder forms.


To learn more about the causes of CdLS click here.


“Characteristics of CdLS.” Cornelia De Lange Syndrome (CdLS) Foundation, Inc.,                         


"Cornelia De Lange Syndrome.” Genetic and Rare Diseases Information Center, U.S. Department                of Health and Human Services,